Table 4.
Laboratory profile.
| Autoimmune gastritis (n=60) | Controls (n=30) | p value | |
|---|---|---|---|
| Laboratory test results, median (IQR) a | |||
| Hematocrit (%) | 38.9 (37.2–42.2) | 40.4 (38.9–41.4) | 0.172 |
| Hemoglobin (g/dL) | 13.1 (12.5–14.2) | 13.7 (13.1–14.2) | 0.152 |
| MCV (f/L) | 88.9 (85.0–93.0) | 88.3 (86.0–93.1) | 0.859 |
| Leukocytes (x 10^3/μL) | 5.9 (4.9–7.0) | 6.4 (5.3–7.6) | 0.185 |
| Platelets (x 10^3/μL) | 267.0 (198.5–301.5) | 274.0 (215.0–320.0) | 0.378 |
| ESR (mm/hr) | 8.0 (5.0–15.5) | 9.0 (5.0–13.0) | 0.976 |
| Vitamin D (ng/mL) | 20.2 (15.6–26.6) | 16.2 (14.0–22.6) | 0.144 |
| Vitamin B12 (pg/mL) | 245.0 (140.0–440.0) | 439.0 (324.0–624.0) | 0.005 |
| Ferritin (ng/mL) | 37.4 (12.6–115.5) | 37.8 (22.1–88.6) | 0.702 |
| Gastrin (pg/mL) | 395.0 (103.0–902.0) | 102.0 (47.0–137.0) | 0.047 |
| Proportion of alteration in laboratory tests, n (%) b | |||
| Hb <12 Female / Hb <13 Male (g/dL) | 15 (25.0) | 3 (11.5) | 0.159 |
| MCV <80 (f/L) | 7 (11.7) | 0 (0.0) | 0.081 |
| MCV >100 (f/L) | 7 (11.7) | 0 (0.0) | 0.081 |
| Vitamin B12 < 200 (pg/mL) | 26 (44.1) | 1 (5.6) | 0.003 |
| Vitamin D < 20 (ng/mL) | 26 (46.4) | 10 (62.5) | 0.257 |
| Vitamin D < 30 (ng/mL) | 46 (82.1) | 15 (93.8) | 0.255 |
| Ferritin < 30 (ng/mL) | 25 (41.7) | 6 (37.5) | 0.763 |
| Iron deficiencyc | 25 (42.4) | 6 (46.2) | 0.071 |
Significant associations confirmed by multivariable logistic regression modeling adjusted for sex, age, H. pylori, tobacco and alcohol consumption. Significance p<0.05.
a
Differences calculated by chi-square test.
b
Differences calculated by Mann-Whitney test.
c
Ferritin <30 ng/mL or transferrin saturation <16%.
MCV: mean corpuscular value; ESR: erythrocyte sedimentation rate; Hb: hemoglobin.