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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Surg Oncol. 2021 Dec 31;40:101696. doi: 10.1016/j.suronc.2021.101696

Table 2.

Multivariable Cox Proportional Hazards Model Analysis for Overall Survival in 56 Patients Who Underwent Resection of ICC*

Variable No. of patients No. of events HR 95% CI P value
Age - - 1.06 1.02–1.11 0.003
Sex
  Male 18 14 3.95 1.76–8.84 < 0.001
  Female 38 20 Reference
Positive lymph nodes
  Yes 7 6 4.45 1.67–11.87 0.003
  No 49 28 Reference
Arterial enhancement pattern
  Hypovascular 10 7 5.33 1.52–19.90 0.009
  Peripherally enhancing 29 20 1.65 0.67–4.09 0.280
  Hypervascular 17 7 Reference

Abbreviations: ICC, intrahepatic cholangiocarcinoma; HR, hazard ratio.

*

A Cox proportional hazards model analysis initially included age (continuous variable), sex, prehepatectomy CA19–9 level (> 37 vs ≤ 37 ng/mL), prehepatectomy chemotherapy, lymph node metastasis, number of ICC (multiple vs single), largest ICC diameter (> 3 vs ≤ 3 cm), and arterial enhancement patter. A backward elimination with a threshold P value of 0.20 was used to select variables for the final models.