Table 3.
Comparison of changes of serum myocardial enzymes and oxidative stress indexes between two groups before and after chemotherapy (X ± S).
Index | Control group | Experiment group | t | p | ||||
---|---|---|---|---|---|---|---|---|
Before chemotherapy | After chemotherapy | Δ∗ | Before chemotherapy | After chemotherapy | Δ∗ | |||
AST (U/L) | 99.82 ± 27.42 | 115.63 ± 36.38 | 16.32 ± 3.26∗ | 98.36 ± 24.62 | 135.26 ± 38.63 | 36.52 ± 5.32∗ | 9.52 | <0.05 |
LDH (U/L) | 151.37 ± 33.64 | 163.52 ± 38.52 | 11.35 ± 2.89∗ | 152.01 ± 32.85 | 169.85 ± 35.65 | 18.62 ± 2.36∗ | 7.98 | <0.05 |
CK (U/L) | 107.67 ± 29.73 | 108.63 ± 29.58 | 1.35 ± 0.28∗ | 107.52 ± 29.33 | 118.63 ± 31.23 | 15.28 ± 2.08∗ | 10.68 | <0.05 |
CK-MB (U/L) | 18.66 ± 6.54 | 20.03 ± 6.66 | 2.33 ± 0.59∗ | 18.72 ± 6.48 | 28.65 ± 7.62 | 12.32 ± 2.65∗ | 10.66 | <0.05 |
α-HBDH (U/L) | 109.66 ± 38.26 | 125.36 ± 42.55 | 17.63 ± 2.21∗ | 109.75 ± 38.42 | 132.56 ± 45.36 | 23.62 ± 4.25∗ | 9.98 | <0.05 |
SOD (U/mL) | 169.21 ± 9.56 | 136.65 ± 8.25 | -30.25 ± 5.38∗ | 169.21 ± 9.56 | 115.36 ± 12.25 | -48.63 ± 8.63∗ | 12.35 | <0.05 |
MDA (nmol/L) | 3.95 ± 0.56 | 12.36 ± 0.85 | 7.56 ± 1.86∗ | 3.95 ± 0.56 | 18.63 ± 3.25 | 15.52 ± 2.63∗ | 6.32 | <0.05 |
Note: Δ represents the change of indicators after chemotherapy compared with before chemotherapy, that is after chemotherapy–before chemotherapy; ∗ represents the comparison between the study group and the control group after chemotherapy.