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Levels of renal function markers during the period of follow up. Urea, Cr, β2-MG, CysC, and eGFR were detected on postoperative day 6 (T1), day 30 (T2), day 60 (T3) and day 90 (T4). #P < 0.05 vs. T1 in Dex group, and &P < 0.05 vs. T1 in Con group. Cr: serum creatinine; β2-MG: β2 microglobulin; CysC: Cystatin C; eGFR: estimated glomerular filtration rate; Dex: group administrated with dexmedetomidine; Con: control group received saline.
