Table 4.
Renal function markers in the first 3 months of following up. Urea, Cr (serum creatinine), β2-MG (β2 microglobulin), CysC (Cystatin C), and eGFR (estimated glomerular filtration rate) were detected on postoperative day 6, day 30, day 60, and day 90. Dex: group administrated with dexmedetomidine; Con: control group received saline. Data are given as the median (SD).
| Dex | Con | P value | |
|---|---|---|---|
| Urea (mmol/L) | n = 32 | n = 29 | |
| Day 6 | 19.478 (13.524) | 17.000 (12.394) | 0.460 |
| Day 30 | 9.796 (4.256) | 9.446 (4.562) | 0.757 |
| Day 60 | 8.116 (2.630) | 8.789 (3.890) | 0.428 |
| Day 90 | 8.613 (3.405) | 8.729 (3.386) | 0.895 |
| Cr (μmol/L) | n = 32 | n = 29 | |
| Day 6 | 279.291 (258.878) | 256.979 (232.773) | 0.726 |
| Day 30 | 154.031 (111.851) | 137.172 (64.783) | 0.480 |
| Day 60 | 142.563 (111.466) | 128.341 (52.974) | 0.534 |
| Day 90 | 153.875 (158.994) | 130.862 (49.771) | 0.458 |
| β2-MG (mg/L) | n = 31 | n = 29 | |
| Day 6 | 5.565 (5.086) | 4.759 (3.723) | 0.489 |
| Day 30 | 3.728 (2.174) | 3.539 (2.049) | 0.730 |
| Day 60 | 3.190 (1.705) | 3.147 (1.796) | 0.924 |
| Day 90 | 3.326 (1.934) | 3.117 (1.559) | 0.647 |
| CysC (mg/L) | n = 31 | n = 29 | |
| Day 6 | 2.509 (1.48478) | 2.317 (1.118) | 0.575 |
| Day 30 | 1.747 (.39242) | 1.888 (.672) | 0.320 |
| Day 60 | 1.889 (.54461) | 1.827 (.501) | 0.648 |
| Day 90 | 1.821 (.50426) | 1.865 (.537) | 0.745 |
| eGFR (ml/min/m2) | n = 31 | n = 29 | |
| Day 6 | 44.081 (27.143) | 49.666 (29.565) | 0.449 |
| Day 30 | 57.490 (22.316) | 60.645 (22.767) | 0.590 |
| Day 60 | 62.239 (20.085) | 63.172 (20.986) | 0.861 |
| Day 90 | 61.242 (21.152) | 61.931 (22.209) | 0.902 |