Table 1.
General and ocular characteristics of diabetic patients in two cohorts.
Cohort 1 | Cohort 2 | |||||
---|---|---|---|---|---|---|
NDR | NPDR | Pvalue | NDR | NPDR | Pvalue | |
Eyes (n) | 71 | 50 | NA | 70 | 50 | NA |
Age (years) | 56.39 ± 11.01 | 57.00 ± 8.83 | 0.749 | 56.83 ± 10.62 | 57.61 ± 9.12 | 0.676 |
Sex (male: female) | 43 : 28 | 31 : 19 | 0.873 | 41 : 29 | 26 : 24 | 0.475 |
HbAlc (%) | 8.63 ± 2.17 | 8.83 ± 2.45 | 0.640 | 8.59 ± 2.09 | 9.22 ± 2.56 | 0.159 |
DM duration (years) | 7.27 ± 6.77 | 11.46 ± 7.58 | 0.003∗ | 7.64 ± 6.92 | 11.50 ± 6.94 | 0.006∗ |
Presence of hypertension (n, %) | 6, 8.45% | 5, 10.00% | 1.000 | 4, 5.71% | 5, 10.00% | 0.598 |
Severity (mild: moderate) | NA | 20 : 30 | NA | NA | 24 : 26 | NA |
IOP (mmHg) | 15.51 ± 2.52 | 15.38 ± 3.69 | 0.822 | 15.48 ± 2.72 | 15.17 ± 3.63 | 0.600 |
BVCA (LogMAR) | -0.0079 ± 0.11 | 0.10 ± 0.21 | <0.001∗ | 0.0020 ± 0.10 | 0.072 ± 0.19 | 0.01∗ |
FAZ area (mm2) | 0.33 ± 0.12 | 0.37 ± 0.24 | 0.153 | 0.37 ± 0.26 | 0.41 ± 0.27 | 0.443 |
SCP density (%) | 46.79 ± 3.83 | 43.71 ± 4.72 | <0.001∗ | 46.51 ± 4.22 | 43.80 ± 4.32 | 0.001∗ |
DCP density (%) | 46.18 ± 6.12 | 43.09 ± 6.32 | 0.008∗ | 45.52 ± 4.87 | 42.17 ± 6.18 | 0.001∗ |
RPCP density (%) | 48.02 ± 3.13 | 46.43 ± 3.04 | 0.007∗ | 47.49 ± 4.00 | 46.27 ± 3.04 | 0.078 |
NDR, nondiabetic retinopathy; NPDR, nonproliferative diabetic retinopathy; NA, not available; DM, diabetes mellitus; IOP, intraocular pressure; BCVA, best corrected visual acuity; FAZ, foveal avascular zone; SCP, superficial capillary plexus; DCP, deep capillary plexus; RPCP, radial peripapillary capillary plexus. ∗P <0.05.