Table 1.

List of mutated antigens that were found or studied in CRC.

Gene	Type of mutation	Epitope	HLA	Reference
OGT	Frameshift mutation	SLYKFSPFPL (FSP06)	HLA-A0201	[48]
TGFβRII	Frameshift mutation	p523, SLVRLSSCV p573, RLSSCVPVA p577, SSCVPVALM p578, LSSCVPVAL p579, VPVALMSAM p537, AMTTSSSQKNITPAILTCC p538, SLVRLSSCVPVALMSAMTTSSSQ p539, ALMSAMTTSSSQKNITPAILTCC p540, SPKCIMKEKKSLRLSSCVPVA p541, PKCIMKEKKKSLVRLSSCV p542, SPKCIMKEKKAW p543, PKCIMKEKKKAW p621, KSLVRLSSCVPVALMSAMT	—	[51], [52], [53]
Bax	Frameshift mutation	p517, RHPSWPWTRCLRMRPPRS p518, IQDRAGRMGGRHPSWPWTRCLR p519, GGTRAGPGPGASGCVHQEAERV p520, ASGCVHQEAERVSQAHRGRTGQ p521, IQDRAGRMGGGGTRAGPGPGAS	—	[51]
MSH3	Frameshift mutation	FLLALWECSL (FSP18) LLALWECSL (FSP19) IVSRTLLLV (FSP23) LIVSRTLLLV (FSP31)	HLA-A0201	[54]
CDX2	Frameshift mutation	—	—	[55]
FTO	Frameshift mutation	TLSPGWSAV	HLA-A0201	[56], [92]
Caspase 5	Frameshift mutation	FLIIWQNTM	HLA-A0201	[56], [93]
KRAS	SNVs	G12D, VVVGADGVGK G12V, VVGAVGVGK G12A, VVVGAAGVGK	HLA-A1101	[65], [70]
PIK3CA	SNVs	—	—	[70]
PARVA	SNVs	NLPLSPIPFELDREDTMLEENEVRT	—	[76]
G3BP1	SNVs	NCHTKIRHVDAHTTLNDGVVVQVMG IRHVDAHTTL	—	[76]
ACTR10	SNVs	SVPEGVLEDIKAHTCFVSDLKRGLK	—	[76]
RAE1	SNVs	WWLETLAQPELFLSTLPHLCTNLGP	—	[76]
PDP1	SNVs	PKSEAKSVVKQDWLLGLLMPFRAFG SEAKSVVKQDW SEAKSVVKQDWL	—	[76]
QRICH1	SNVs	VHVSGSPTALAAFKLEDDKEKMVGT	—	[76]