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. 2022 Feb 17;28(2):283–294. doi: 10.1038/s41591-022-01682-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a, Top: Table describing the patient groups in the Translink study. This included three groups of BHV recipients (groups A, B1 and B2) and control patients who were treated with MHV replacement surgery or CABG. Bottom: Timeline of patients enrollment and follow-up. b, Distribution of BHV brands implanted into patients in groups B1 and B2. c, Flowcharts describing the two arms (BHV patients and control patients) in groups B1 and B2. The total number of patients who remained in the study after hospital discharge for group B1 or after the inclusion visit for group B2 is shown (gray dashed boxes). The number of BHV recipients who had an echocardiography at the end of the group B1 follow-up are shown (blue dashed box).