Table 3.
Cost-Benefit Estimates and Quality
| Study author (year) | Design | Intervention cost PPPY (A) | Total benefit PPPY (B) | Benefit to cost ratio (B/A) | Quality of benefit to cost ratio estimate |
|---|---|---|---|---|---|
| Basu (2012)a41 | RCT | $4,368 | $12,624 | 2.9 | F |
| Basu (2012)b41 | RCT | $4,177 | $17,016 | 4.1 | G |
| Basu (2012)c41 | RCT | $5,525 | $14,193 | 2.6 | F |
| Culhane (2002)43 | PPMC | $20,830 | $18,640 | 0.9 | G |
| Flaming (2009)a54 | PPMC | $15,737 | $32,715 | 2.1 | F |
| Flaming (2009)b54 | PPMC | $15,651 | $36,014 | 2.3 | F |
| Flaming (2009)c54 | PPMC | $15,951 | $34,558 | 2.2 | F |
| Flaming (2009)d54 | PPMC | $16,051 | $44,625 | 2.8 | F |
| Flaming (2013)44 | WLC | $32,955 | $52,193 | 1.6 | G |
| Gilmer (2010)47 | PPMC | $3,921a | $1,312 | 0.3 | F |
| Larimer (2009)50 | WLC | $17,069 | $54,392 | 3.2 | G |
| Seligson (2013)a51 | PPMC | $16,873 | $17,854 | 1.1 | G |
| Seligson (2013)b51 | PPMC | $29,105 | $37,630 | 1.3 | G |
| Seligson (2013)c51 | PPMC | $29,154 | $28,729 | 1.0 | G |
| Seligson (2013)d51 | PPMC | $25,567 | $12,344 | 0.5 | G |
| Srebnik (2013)56 | PPC | $20,274a | $35,705 | 1.8 | G |
| Toros (2012)57 | PPC | $34,104 | $26,907 | 0.8 | F |
| Goering (2014)a58 | RCT | $20,143 | $19,344 | 1.0 | G |
| Goering (2014)b58 | RCT | $12,830 | $4,388 | 0.3 | F |
| Latimer (2019)59 | RCT | $11,553 | $1,993 | 0.2 | F |
| Patterson (2008)a60 | Modeled | $16,586 | $17,750 | 1.1 | F |
| Patterson (2008)b60 | Modeled | $14,994 | $17,750 | 1.2 | F |
| Patterson (2008)c60 | Modeled | $19,249 | $17,750 | 0.9 | F |
| Summary Median (IQI) | — | U.S. studies $16,873 (IQI: $15,651 to $25,567) U.S. studies with good quality $20,830 (IQI: $17,069 to $29,105) All studies $16,586 (IQI: $13,912 to $20,552) |
U.S. studies $28,729 (IQI: $17,016 to $36,014) U.S. studies with good quality $28,729 (IQI: $17,854 to $37,630) All studies $18,640 (IQI: $15,605 to $35,132) |
U.S. studies 1.80 (IQI: 1.00 to 2.60) U.S. studies with good quality $1.3 (IQI: $1.0 to $1.8) All studies 1.06 (IQI: 0.87 to 1.84) |
— |
a
Does not include management and overhead costs.
PPMC, pre post with matched control; PPC, pre post with control; WLC, wait list control; PPPY, per person per year; NR, not reported; NA, not applicable; PPPY, per person per year; G, good; F, fair; IQI, interquartile interval.