Table 3.
Associations of type surgical approach and amount of blood lost with Clavien–Dindo complications after prostate cancer surgery by subgroups stratifying cases without and with extended pelvic lymph node dissection
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Subgroups | CDS 1–2 vs. CDS = 0 | CDS > 2 vs. CDS = 0 | CDS > 2 vs. CDS 1–2 | CDS 1–2 vs. CDS = 0 | CDS > 2 vs. CDS = 0 | CDS > 2 vs. CDS 1–2 |
| No ePLND | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) |
| RARP | 1 | 1 | 1 | 1 | 1 | 1 |
| ORP | 3699 (1207—11333) | 19,286 (4110–90,505) | 5214 (1065–25,522) | 3139 (1002–9840) | 18,339 (3742–89,874) | 5214 (1065–25,522) |
| p value | 0.022 | < 0.0001 | 0.042 | 0.048 | < 0.0001 | 0.042 |
| BL ≤ 600 mL | 1 | 1 | 1 | 1 | 1 | 1 |
| BL > 600 mL | 2178 (1150–4126) | 1986 (0.406–9718) | 0.912 (0.177–4699) | 2004 (1045–3844) | 1270 (0.231–6982) | 0.634 (0.112–3598) |
| p value | 0.017 | 0.397 | 0.912 | 0.036 | 0.783 | 0.607 |
| ePLND | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) |
| RARP | 1 | 1 | 1 | 1 | 1 | 1 |
| ORP | 1683 (1111––2550) | 7521 (3991–14,175) | 4468 (2278–8763) | 1506 (1010–2428) | 6964 (3568–13,512) | 4446 (2179–9072) |
| p value | 0.014 | < 0.0001 | < 0.0001 | 0.045 | < 0.0001 | < 0.0001 |
| BL ≤ 600 mL | 1 | 1 | 1 | 1 | 1 | 1 |
| BL > 600 mL | 1505 (0.952–2380) | 2698 (1385–5257) | 1792 (0.877–3661) | 1298 (0.792–2093) | 1308 (0.632–2709) | 1016 (0.471—2193) |
| p value | 0.080 | 0.004 | 0.109 | 0.308 | 0.469 | 0.967 |
OR odds ratio; CI confidence interval; RARP robot-assisted radical prostatectomy; ORP open radical prostatectomy; ePLND extended pelvic lymph node dissection; BL, blood lost