Table 1.
Patient characteristics.
| Characteristics | High-CRPmax (n = 258) | Low-CRPmax (n = 186) |
p value | High-WBCmax (n = 83) |
Low-WBCmax (n = 361) |
p value |
|---|---|---|---|---|---|---|
| Age (years) | 0.909 | 0.775 | ||||
| < 75 | 199 (77.1%) | 142(76.3%) | 65 (78.3%) | 276 (76.5%) | ||
| ≥ 75 | 59 (22.9%) | 44 (23.7%) | 18 (21.7%) | 85 (23.5%) | ||
| Sex | 0.136 | 0.336 | ||||
| Male | 195 (75.6%) | 109 (58.6%) | 61 (67.3%) | 243 (73.5%) | ||
| Female | 63 (24.4%) | 77 (41.4%) | 22 (32.7%) | 118 (26.5%) | ||
| BMI (kg/m2) | 0.141 | 0.852 | ||||
| < 18.5 | 26 (10.1%) | 28 (15.1%) | 9 (10.8%) | 45 (12.5%) | ||
| ≥ 18.5 | 232 (89.9%) | 158 (84.9%) | 74 (89.2%) | 316 (87.5%) | ||
| PS | 0.658 | 0.566 | ||||
| 0 | 201 (77.9%) | 149 (80.1%) | 63 (75.9%) | 287 (79.5%) | ||
| 1–2 | 57 (22.1%) | 37 (19.9%) | 20 (24.1%) | 74 (20.5%) | ||
| Operative approach | 0.113 | 0.326 | ||||
| Open | 246 (95.3%) | 170 (91.4%) | 80 (96.4%) | 236 (93.1%) | ||
| Laparoscopic | 12 (4.7%) | 16 (8.6%) | 3 (3.6%) | 25 (6.9%) | ||
| Operative procedure | < 0.001 | < 0.001 | ||||
| DG, PG | 122 (46.9%) | 140 (75.3%) | 24 (28.9%) | 238 (65.7%) | ||
| TG | 136 (52.7%) | 46 (24.7%) | 59 (71.1%) | 123 (34.1%) | ||
| Operation time (min) | 230 [199–282] | 194 [171–233] | < 0.001 | 250 [204–293] | 210 [180–248] | < 0.001 |
| Blood loss (ml) | 448 [290–660] | 253 [150–394] | < 0.001 | 530 [310–778] | 330 [190–500] | < 0.001 |
| Tumor size (mm) | 55 [15–200] | 45 [10–130] | < 0.001 | 64 [15–90] | 50 [10–200] | < 0.001 |
| Depth of invasion | 0.221 | 0.248 | ||||
| T1–2 | 45 (17.4%) | 42 (22.6%) | 12 (14.5%) | 75 (20.8%) | ||
| T3–4 | 213 (82.6%) | 144 (77.4%) | 71 (85.5%) | 286 (79.2%) | ||
| Lymph node metastasis | 0.285 | 0.89 | ||||
| N0 | 66 (25.6%) | 57 (30.6%) | 24 (28.9%) | 99 (27.4%) | ||
| N1–3 | 192 (74.4%) | 129 (69.4%) | 59 (71.1%) | 262 (72.6%) | ||
| pStage† | 0.106 | 0.229 | ||||
| II | 123 (47.7%) | 104 (55.9%) | 37 (44.6%) | 190 (52.6%) | ||
| III | 135 (52.3%) | 82 (44.1%) | 46 (55.4%) | 171 (47.4%) | ||
| Tumor location | < 0.001 | < 0.001 | ||||
| U | 98 (38.0%) | 31 (16.7%) | 38 (45.8%) | 91 (25.2%) | ||
| M | 68 (26.4%) | 80 (43.0%) | 20 (24.1%) | 128 (35.5%) | ||
| L | 79 (30.6%) | 71 (38.2%) | 17 (20.5%) | 133 (36.8%) | ||
| UML | 13 (5.0%) | 4 (2.2%) | 8 (9.6%) | 9 (2.5%) | ||
| Histology | 0.408 | 0.135 | ||||
| Differentiated | 121 (46.9%) | 79 (42.5%) | 44 (53.0%) | 156 (43.2%) | ||
| Undifferentiated | 137 (53.1%) | 107 (58.5%) | 39 (47.0%) | 205 (56.8%) | ||
| Postoperative infectious complication* | < 0.001 | < 0.001 | ||||
| Absent | 190 (73.6%) | 183 (98.4%) | 45 (54.2%) | 328 (90.9%) | ||
| Present | 68 (26.4%) | 3 (1.6%) | 38 (45.8%) | 33 (9.1%) | ||
| Adjuvant chemotherapy | 0.526 | 0.804 | ||||
| Absent | 60 (23.3%) | 49 (26.3%) | 19 (22.9%) | 90 (26.3%) | ||
| Present | 198 (76.7%) | 137 (73.7%) | 64 (77.1%) | 271 (73.7%) |
Values in parentheses are percentages unless indicated otherwise; values are all median (i.q.r.)
BMI body mass index, PS performance status, DG distal gastrectomy, PG proximal gastrectomy, TG total gastrectomy, U upper, M middle, L lower.
†According to the 7th edition of the International Union Against Cancer.
*Intra-abdominal abscess, anastomotic leakage, pancreatic fistula, pneumonia, surgical site infection, acute cholecystitis, and enteritis Grade ≥ 2 based on the Clavien-Dindo classification.