Table 1.
Liver pathology score.
Parameter | C | N | NP |
---|---|---|---|
NAS | 0.0 ± 0.0 | 7.3 ± 0.8a | 2.3 ± 1.2b |
Steatosis | 0.0 ± 0.0 | 2.5 ± 0.5a | 1.2 ± 0.4b |
Lobular inflammation | 0.0 ± 0.0 | 2.8 ± 0.4a | 0.5 ± 0.5b |
Hepatocyte ballooning | 0.0 ± 0.0 | 2.0 ± 0.0a | 0.7 ± 0.5b |
Fibrosis | 0.2 ± 0.2 | 3.2 ± 0.4a | 0.5 ± 0.5b |
The nonalcoholic fatty liver disease activity score (NAS) and fibrosis stage were scored.
Results are presented as the mean ± SD, and p values were calculated using one-way ANOVA with Tukey’s post hoc test. aP < 0.001, C vs. N group or bP < 0.001, N vs. NP group. The number of mice in each group: C, n = 6; N, n = 6; NP, n = 6.