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. 2022 Feb 22;12:2991. doi: 10.1038/s41598-022-06956-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Summary of analysis of EXAMIN AGE data. (A). Distribution of the number of individual miRNAs detected in specific numbers of samples and number and percentage of mature miRs identified in the indicated proportions of samples. (B). Numbers of miRNAs with specific values of median expression across samples (miRNAs with zero median expression are not shown). (C). Outline of the comparison of miRNA expression between groups of patients. DEA differential expression analysis, HA healthy active, HS healthy sedentary, SR sedentary at increased CV risk, FC fold change, FDR false discovery rate.