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. 2022 Feb 22;12:2991. doi: 10.1038/s41598-022-06956-4

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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miRNA expression changes between conditions. (A) ‘Volcano plots’ showing the fold-change versus statistical significance measure for pairs of sample groups. (B) Mean versus fold-change expression of individual miRNAs in pairs of sample groups. HA healthy active, HS healthy sedentary, SR sedentary at increased CV risk, FDR false discovery rates, CPM count-per-million.