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. 2022 Feb 22;8:77. doi: 10.1038/s41420-022-00850-8

Fig. 10. Mechanism graph of lncRNA SNHG1 modulating the miR-15a/SMURF1/UVRAG/ATG5/Wnt5a axis in HLC differentiation of BMSCs and cirrhosis.

Fig. 10

shRNA-mediated lncRNA SNHG1 silencing promotes HLC differentiation of BMSCs to alleviate cirrhosis by activating UVRAG/ATG5/Wnt5a axis via downregulation of miR-15a-targeted SMURF1.