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. 2022 Feb 22;8:77. doi: 10.1038/s41420-022-00850-8

Fig. 9. SMURF1/UVRAG/ATG5/Wnt5a axis affects cirrhosis in mice.

Fig. 9

A RT-qPCR to detect the expression of hepatocyte-related genes in BMSCs after simultaneous treatment of oe-SMURF1 and oe-UVRAG, rapamycin, or recombinant Wnt5a for 14 days. B ELISA to detect the secretion of ALB by BMSCs after simultaneous treatment of oe-SMURF1 and oe-UVRAG, rapamycin, or recombinant Wnt5a for 14 days. C PAS staining of glycogen accumulation in BMSCs after simultaneous treatment of oe-SMURF1 and oe-UVRAG, rapamycin, or recombinant Wnt5a for 14 days. *p < 0.05 vs. BMSCs transfected with oe-NC; #p < 0.05 vs. BMSCs transfected with oe-SMURF1. The cell experiments were repeated three times.