Table 6.
Cross-lagged standard regression coefficient of RC and blood pressure levels in the sensitivity analyses.
| Sensitivity tests | Variables | Model | βRC-blood pressure(95% CI) | βblood pressure-RC(95% CI) | p-value a | CFI |
|---|---|---|---|---|---|---|
| I | SBP | Model 1 b | 0.047 (0.035,0.059) | 0.028 (0.016,0.040) | <0.001 | 0.920 |
| Model 2 c | 0.035 (0.023,0.047) | 0.023 (0.011,0.035) | <0.001 | 0.928 | ||
| DBP | Model 1 b | 0.092 (0.081,0.104) | 0.026 (0.014,0.037) | <0.001 | 0.922 | |
| Model 2 c | 0.081 (0.069,0.093) | 0.024 (0.012,0.035) | <0.001 | 0.930 | ||
| MAP | Model 1 b | 0.075 (0.064,0.087) | 0.028 (0.017,0.040) | <0.001 | 0.916 | |
| Model 2 c | 0.066 (0.054,0.077) | 0.025 (0.013,0.037) | <0.001 | 0.925 | ||
| II | Hypertension | Model 3 d | 0.030 (0.018,0.042) | 0.020 (0.008,0.032) | <0.001 | 0.936 |
| SBP | Model 3 d | 0.034 (0.022,0.046) | 0.025 (0.013,0.037) | <0.001 | 0.928 | |
| DBP | Model 3 d | 0.077 (0.065,0.089) | 0.019 (0.007,0.031) | <0.001 | 0.930 | |
| MAP | Model 3 d | 0.063 (0.051,0.074) | 0.023 (0.011,0.035) | <0.001 | 0.925 | |
| III | Hypertension | Model 4 e | 0.035 (0.022,0.048) | 0.009 (-0.004,0.021) | <0.001 | 0.936 |
| SBP | Model 4 e | 0.039 (0.027,0.052) | 0.016 (0.004,0.029) | <0.001 | 0.926 | |
| DBP | Model 4 e | 0.088 (0.076,0.101) | 0.018 (0.005,0.030) | <0.001 | 0.927 | |
| MAP | Model 4 e | 0.071 (0.058,0.083) | 0.018 (0.006,0.031) | <0.001 | 0.921 |
RC, remnant cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; CI, confidence interval; CFI, comparative fit index.
Test the difference of the cross-lagged path coefficients between βRC-blood pressure and βblood pressure-RC by the t-test.
In Model 1, the adjustment factors included age, sex, and heart rate.
In Model 2, the adjustment factors included age, sex, heart rate, body mass index, fasting blood glucose, alanine aminotransferase, leukocyte count, and serum creatinine.
In Model 3, the adjustment factors included age, sex, heart rate, body mass index, fasting blood glucose, alanine aminotransferase, leukocyte count, serum creatinine, and low-density lipoprotein cholesterol.
In Model 4, the adjustment factors included age, sex, heart rate, fasting blood glucose, alanine aminotransferase, leukocyte count, and serum creatinine.