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. 2022 Feb 22;13:863. doi: 10.1038/s41467-022-28426-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Comparison between the relative cell abundances of cOTUs detected from the distal location and proximal location of the mouse VSa, shown in Fig. 4a (other mice in Supplementary Fig. 16a). b Proportion of location-dependent differentially abundant cOTUs (differences were larger than the sampling noise and 2-fold) in each mouse. Technical, all pairs from three technical replicates within the distal and proximal locations for the mouse CEa; CE2, the mice in the CE2 nutriment group; VA-suf, the mice in the VA-sufficient group; VA-def, the mice in the VA-deficient group. Boxes represent 25th to 75th percentiles (the interquartile range), horizontal black lines indicate medians, and whiskers show 1.5 times the interquartile range (n = 6 for Technical, n = 3 for CE2, n = 4 for VA-suf and VA-def). P values were calculated by the Kruskal–Wallis rank-sum test. Source data are provided as a Source Data file.