Table 1.
The clinical characteristics of the cross-sectional cohort grouped by presence or absence of NAFLD are shown.
| Youth without NAFLD (n = 89) | Youth with NAFLD (n = 86) | P-value | |
|---|---|---|---|
| Age (y) | 13.1 ± 3.09 | 13.6 ± 3.03 | 0.224 |
| Sex (M/F) | (27/62) | (42/44) | 0.174 |
| Ethnicity (C/AA/H/O) | 21/35/29/4 | 17/8/54/7 | <1.0 × 10−10 |
| BMIz | 2.23 ± 0.461 | 2.37 ± 0.367 | 0.145 |
| Fasting glucose (mg/dL) | 90 ± 7 | 92 ± 8 | 0.039 |
| Fasting insulin (mU/L) | 31 ± 24 | 41 ± 26 | 2.32 × 10−4 |
| 2-h glucose (mg/dL) | 119 ± 28 | 129 ± 32 | 0.029 |
| WBISI | 2.25 ± 1.14 | 1.56 ± 0.895 | 3.65 × 10−5 |
| Triglycerides (mg/dL) | 103 ± 43.8 | 170 ± 145 | 3.75 × 10−4 |
| HDL (mg/dL) | 43.1 ± 8.48 | 40.5 ± 10.5 | 0.044 |
| LDL (mg/dL) | 93.8 ± 27.5 | 97.9 ± 24.5 | 0.361 |
| Total cholesterol (mg/dL) | 161 ± 30.5 | 169 ± 40.7 | 0.316 |
| ALT (IU/L) | 21.7 ± 25.3 | 60.1 ± 74.3 | <1.0 × 10−10 |
| HFF % | 1.92 ± 1.71 | 16.9 ± 10.4 | <1.0 × 10−10 |
| VAT (cm2) | 64.3 ± 27.5 | 91.1 ± 36.9 | 5.84 × 10−6 |
| SAT (cm2) | 514 ± 194 | 519 ± 186 | 0.966 |
| VAT/VAT+SAT | 0.114 ± 0.038 | 0.153 ± 0.047 | 2.22 × 10−7 |
A Mann–Whitney test was used to compare the differences between subjects with and without NAFLD. Glucose, insulin, triglycerides, HDL, LDL, total cholesterol, and ALT were measured from plasma. Data are shown as mean ± standard deviation.
AA African American, C Caucasian, F female, H Hispanic, M male, O Other, WBISI whole body insulin sensitivity index.
Italics values identify statistical significance.