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. 2022 Feb 9;13:851004. doi: 10.3389/fimmu.2022.851004

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Copyright © 2022 Guo, Xie and Luo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LncRNA and innate immune cells in TIME. LncRNA is central player in cancer biology and they play a pivotal role in mediating the network communication between tumor cells and their microenvironment. Innate immune effectors including neutrophils, macrophages, NK cells, DCs, and MDSCs. LncRNA can interact with tumor-infiltrating innate immune cells to modulate their recruitment, development and function in tumor microenvironment. Created with BioRender.com.