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. 2022 Feb 9;9:781207. doi: 10.3389/fcvm.2022.781207

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Copyright © 2022 Guo, Liu, Yu, Zhou, Ma, Zhang, Dang, Liu, Wang, Zhang, Hua, Han and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Screening and verification of diagnostic markers based on machine learning. (A,B) LASSO logistic regression algorithm to screen diagnostic markers. (C) SVM-RFE algorithm to screen diagnostic markers. (D) RF algorithm to screen diagnostic markers. (E) Venn diagram shows the intersection of diagnostic markers obtained by the three algorithms. (F) The ROC curve of the diagnostic efficacy verification after fitting two diagnostic markers to one variable.