Table 4.

Effectiveness of osmotherapy with hypertonic saline vs. hypertonic lactate on arterial blood variables.

Variables	Baseline	Post-osmotherapy	P value
Chloride, mmol/L
Hypertonic saline	111 ± 6	115 ± 6	< 0.001
Hypertonic lactate	114 ± 6	113 ± 6	0.233
Sodium, mmol/L
Hypertonic saline	140.4 ± 4.2	143.4 ± 3.9	0.002
Hypertonic lactate	142.4 ± 5.1	144.7 ± 4.4	0.015
pH
Hypertonic saline	7.39 ± 0.04	7.38 ± 0.05	0.269
Hypertonic lactate	7.42 ± 0.04	7.46 ± 0.03	0.009
Lactate, mmol/L
Hypertonic saline	1.5 ± 1.3	1.4 ± 1.1	0.717
Hypertonic lactate	1.0 ± 0.6	2.9 ± 2.6	< 0.001
PaCO2, mmHg
Hypertonic saline	36.4 ± 3.6	37.3 ± 3.1	0.428
Hypertonic lactate	34 ± 3.5	34.7 ± 3.3	0.537

Data are presented as mean ± standard deviation. P values for comparisons of baseline vs. post osmotic agent treatment (ANOVA for repeated measures).

PaCO₂ partial pressure of carbon dioxide.