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. 2022 Feb 23;6(5):303–312. doi: 10.1016/S2352-4642(22)00028-1

Table 2.

SARS-CoV-2 laboratory testing in 21 individuals with MIS-C who had received a COVID-19 vaccine

Total Onset after first dose of COVID-19 vaccine Onset after second dose of COVID-19 vaccine
MIS-C 21 11 (52%) 10 (48%)
With evidence of SARS-CoV-2 infection 15 10 (67%) 5 (33%)
Positive NAAT (past or recent)* 10 5 (50%) 5 (50%)
Negative NAAT and positive anti-nucleocapsid antibody test 5 4 (80%) 1 (20%)
Without evidence of SARS-CoV-2 infection 6 1 (17%) 5 (83%)

Data are n or n (%). MIS-C=multisystem inflammatory syndrome in children. NAAT=nucleic acid amplification test.

*

Includes five individuals with positive SARS-CoV-2 NAAT before MIS-C illness, four with positive SARS-CoV-2 NAAT during MIS-C illness, and one with a positive SARS-CoV-2 NAAT before and during MIS-C illness.

Negative NAAT, negative anti-nucleocapsid antibody test, and positive anti-spike antibody test during MIS-C illness evaluation; these individuals did not have any reported positive NAAT results before MIS-C illness.