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. 2022 Feb 22;13:1003. doi: 10.1038/s41467-022-28662-5

Fig. 4. TRF influences the daily rhythm amplitude of clock genes expression in peripheral blood mononuclear cells.

Fig. 4

After Cosinor analysis, the amplitudes of clock gene expression in each individual were calculated. a The change in amplitude of clock genes after analyzed with Cosinor analysis in eTRF group. All participants in eTRF group showed an increase in the amplitude of SIRT1 after the trial. b The change in amplitude of clock genes after analyzed with Cosinor analysis in mTRF group. All participants in mTRF group showed an increase in the amplitude of PER2, but a decrease in that of PER1 after the trial. c The change in amplitude of clock genes after analyzed with Cosinor analysis in control group.