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. 2022 Feb 9;9:793452. doi: 10.3389/fped.2021.793452

Table 4.

Adjusted associations between risk factors and asthma symptoms by multivariate analyses.

Factors Ever asthma Current asthma
aOR (95% CI) p aOR (95% CI) p
Community 1.03 (1.01, 1.06) 0.008 1.03 (1.01, 1.06) 0.019
Sex
    Male 1.00 1.00
    Female 0.82 (0.70, 0.96) 0.012 0.85 (0.71, 1.01) 0.069
History of allergic rhinitis 1.86 (1.53, 2.25) <0.001 1.89 (1.52, 2.34) <0.001
History of eczema 1.30 (1.09, 1.56) 0.004 1.34 (1.09, 1.64) 0.005
History of food allergy 1.57 (1.31, 1.89) <0.001 1.68 (1.37, 2.06) <0.001
Antibiotics use (1st year) 1.68 (1.41, 2.00) <0.001 1.53 (1.25, 1.87) <0.001
Paracetamol use (1st year) 1.26 (1.06, 1.51) 0.010 1.21 (0.99,1.48) 0.060
Frequency of paracetamol use
    Never 1.00 1.00
    >Once/year 1.16 (0.91, 1.47) 0.223 1.29 (0.97, 1.71) 0.077
    >Once/month 1.44 (1.01, 2.04) 0.043 2.06 (1.39, 3.04) <0.001
Maternal rhinitis 2.18 (1.71, 2.78) <0.001 1.94 (1.48, 2.54) <0.001
Maternal asthma 4.06 (2.57, 6.41) <0.001 3.85 (2.40, 6.17) <0.001
Maternal eczema 1.37 (0.94, 2.00) 0.104 1.42 (0.93, 2.16) 0.104
Paternal rhinitis 1.76 (1.39, 2.22) <0.001 1.67 (1.29, 2.16) <0.001
Paternal asthma 4.89 (3.23, 7.40) <0.001 5.91 (3.87, 9.01) <0.001
Smoking exposure at home 1.05 (0.88, 1.25) 0.558 1.10 (0.91, 1.35) 0.328
Pets at home 1.12 (0.88, 1.41) 0.358 1.09 (0.83, 1.42) 0.550
Pets at home (1st year) 1.07 (0.82, 1.40) 0.614 1.13 (0.83, 1.52) 0.438
Dampness or mildew 1.50 (1.15, 1.97) 0.003 1.63 (1.21, 2.19) 0.001
Cleaning house
    Everyday 1.00 1.00
    Twice/week 1.24 (1.02, 1.51) 0.031 1.12 (0.89, 1.40) 0.334
    Once/week 1.34 (1.09, 1.64) 0.006 1.24 (0.98, 1.57) 0.080
    Once/two week 1.59 (1.04, 2.43) 0.031 1.49 (0.92, 2.41) 0.108
    Once/month 1.24 (0.70, 2.20) 0.458 1.62 (0.90, 2.91) 0.111
     < Once/month 1.36 (0.70, 2.63) 0.362 1.20 (0.56, 2.55) 0.641
Truck traffic in home's street
    Never 1.00 1.00
    Occasionally 1.15 (0.93, 1.41) 0.193 0.98 (0.77, 1.24) 0.862
    Frequently 1.17 (0.87, 1.58) 0.304 1.10 (0.79, 1.53) 0.582
    Almost always 1.32 (0.89, 1.96) 0.172 1.22 (0.78, 1.90) 0.388
Floor heating system 1.57 (1.25, 1.98) <0.001 1.36 (1.04, 1.78) 0.025
Floor
    Solid wood 0.98 (0.71, 1.35) 0.900 0.94 (0.66, 1.35) 0.741
    Laminated flooring 1.06 (0.75, 1.49) 0.730 0.94 (0.64, 1.39) 0.762
Emulsion paint 1.14 (0.98, 1.33) 0.098 1.00 (0.84, 1.20) 0.999

aOR, adjusted odds ratio; CI, confidence interval; 1st year, in the first year of life. Odds ratios shown in the table were adjusted for all other risk/protective factors listed by multivariate logistic regression. Bold font means statistical significance (p < 0.05).