Table 2.

Meta-analyses of anesthetic technique and breast cancer recurrence.

Ref. (year)	Cancer type (patient n)	Surgery type	Anesthetic technique	Outcomes	Benefit/remarks
111 (2017)	Gastrointestinal, breast, prostate, ovarian (n = 67,577)	Cancer surgery	RA/inhalation anesthesia vs. inhalation anesthesia	No difference in OS, RFS, or BRFS Some benefit of OS in RCT on colorectal cancer	Negative
112 (2019)	Breast, esophageal, NSLC (n = 7866) Breast, colorectal, gastric, esophageal, NSLC, mixed (n = 18,778)	Radical cancer surgery	Propofol TIVA vs. inhalation anesthesia	Improved RFS with TIVA Improved OS with TIVA	Positive

RCT, randomized controlled trial; NSLC, non-small cell lung cancer; BRFS, biochemical recurrence-free survival.