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. 2021 Sep 14;19(3):437–451. doi: 10.1016/j.gpb.2021.07.003

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© 2021 Beijing Institute of Genomics

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Dissection of the asynchronous development of keratinocytes

A. Heatmap illustrating gene expression dynamics during keratinocyte differentiation. B. GO terms corresponding to the gene sets shown in (A). Arrows indicate the elongation of pseudotime. C. Expression of cell fate 1 characteristic genes KRT14 and KRT17, and cell fate 2 characteristic genes TOP2A and PCNA along the pseudotime trajectory. D. Immunofluorescence analysis of VDR, PCNA, CTNNB1, BMP2, LEF1, and K15 in E90 cashmere goat skin tissues. Scale bar = 50 μm.