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. 2021 Dec 30;19(3):452–460. doi: 10.1016/j.gpb.2021.07.005

Table 1.

GSEA results on clusters from UMAP plot inFigure 3B

Comparing pair KEGG gene set name Gene set size NES P value FDR
Cluster 2 vs. rest Glycolysis gluconeogenesis 13 4.23 0 0
Pathogenic Escherichia coli infection 14 3.63 0 0
Alzheimer’s disease 20 3.97 0 0
Tight junction 16 3.03 0.004 0.0063



Cluster 3 vs. rest Oocyte meiosis 15 3.75 0 0
Pathogenic Escherichia coli infection 14 3.48 0.001 0.0315
Cell cycle 20 3.13 0.002 0.042
Ubiquitin-mediated proteolysis 12 3.29 0.005 0.0787



Cluster 4 vs. rest Spliceosome 13 3.84 0 0
Viral myocarditis 25 3.23 0.002 0.042



Cluster 5 vs. rest Alzheimer’s disease 20 3.08 0 0
Antigen processing and presentation 30 2.51 0.003 0.0472
MAPK signaling pathway 45 2.91 0 0
Glycolysis gluconeogenesis 13 2.49 0.043 0.198
Spliceosome 13 2.99 0.004 0.0504

Note: GSEA, gene set enrichment analysis; UMAP, uniform manifold approximation and projection; KEGG, Kyoto Encyclopedia of Genes and Genomes; NES, normalized enrichment score; FDR, false detection rate.