Figure 2.

miRNAs with a large target pool are associated with better noise suppression

A. AES score of the Mann–Whitney U test versus the number of targets across all detected miRNAs in mESCs. Curves were fitted to $a+b{\log }_{10}(x+c)$, where $a$, $b$, and $c$ were determined by least-squares approximation. The fitted parameters are shown in Table S1. The cut-off for the AES score is 2.0, and the cut-off for the number of targets is 700 in Fisher’s exact test. B. Similar points and fitting curve to those shown in (A) for target pool abundance. The cut-off for the AES score is 2.0, and the cut-off for the target pool abundance is 16,000.