Supplementary figure 3.

The correlation between effect size and sample size for the Mann–Whitney U test after correction. A. Effect size versus test sample size (the number of targets) for real data. This result shows that there was a noise bias for all three cell line datasets. Effect size less than 0.5 indicates that the local rank CV of miRNA target genes is smaller than non-targets. B. An additional effect size correction step for real data.