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The number of de-noising miRNAs and AES score are not sensitive to GC content of non-target genes. A. The curves show the number of significant de-noising miRNAs varying with GC content threshold. This is used to select the non-miRNA target genes of lower GC content. The colors indicate different cell types. B. Noise disparity between the target genes and non-target genes for shared de-noising miRNAs of three different cell types. The GC content threshold is 0.5.
