Table 1.
Agent | Target | Class | Stage | Active clinical trials | References |
---|---|---|---|---|---|
18F- AraG | Deoxyguanosine kinase (dGK) | Small Molecule | Clinical | NCT04052412, NCT03142204, NCT04186988, NCT03129061, NCT03684655, NCT03367962 | 10, 11, 135 |
18F-CFA | dCK | Small Molecule | Clinical | NCT03409419 | 136 |
1-L-18F-FETrp | IDO | Small Molecule | Preclinical | 137 | |
18F-FAC | Deoxycytidine kinase (dCK) | Small Molecule | Clinical | 8 | |
68Ga-WL12 | PD-L1 PD-L1 PD-L1 PD-L1 PD-L1 PD-L1 |
Peptide | Preclinical | 138 | |
18F-FPy-WL12 | Peptide | Preclinical | 24 | ||
18F-NOTA-ZPD-L1_1 | Affibody | Preclinical | 139 | ||
64Cu-DOTA-FN3hPD-L1 | Adnectin | Preclinical | 140 | ||
68Ga-NOTA-Nb109 | Nanobody | Preclinical | 141 | ||
64Cu-DOTA-HAC-PD1 | High-affinity PD-1 ectodomain | Preclinical | 142, 143 |