Table 3.
Reporter gene imaging T-cells
| Agent | Reporter gene | Species | Type | Stage | |
|---|---|---|---|---|---|
| 18F-FHBG | Herpes Simplex Virus - Thymidine Kinase (HSV-TK) | Herpes Simplex Virus 1 | Enzyme | Clinical | 162, 163 |
| 18F-DCFPyL | Glutamate carboxypeptidase 2 (PSMA) | Human | Cell surface enzyme | Preclinical | 58 |
| 99mTcO4- | Sodium Iodine Symporter (NIS) | Human | Transporter | Preclinical | 49 |
|
123I-MIBG, 124I-MIBG |
Norepinephrine Transporter (NET) | Human | Cell surface receptor | Preclinical | 50 |
| 68Ga-DOTATOC | Somatostatin Receptor 2 (SSTR2) | Human | Cell surface receptor | Preclinical | 51 |
| 18F-TMP | Dihydrofolate reductase enzyme (DHFR) | Escherichia coli | Enzyme | Preclinical | 164 |