Table 6.
Comparison between MTC patients with and without lateral LNM.
| lateral LNM | P-value | ||
|---|---|---|---|
| yes (n = 65) | no (n = 87) | ||
| Male (n) | 29 (44.6%) | 30 (34.5%) | 0.205 |
| Age (years) | 47.0 ± 11.8 | 46.1 ± 12.8 | 0.643 |
| BMI ≥28 (kg/m2) | 7 (10.8%) | 9 (10.3%) | 0.933 |
| Hereditary (n) | 13(20.0%) | 14 (16.1%) | 0.533 |
| Hashimoto's disease (n) | 6 (9.2%) | 15 (17.2%) | 0.157 |
| Calcitonin ˃500 pg/mL (n) | 19 (29.2%) | 11 (12.6%) | 0.011 |
| CEA ˃50 ng/mL (n) | 21 (32.3%) | 9 (10.3%) | 0.001 |
| ASA ≥III (n) | 3 (4.6%) | 2 (2.3%) | 0.428 |
| Postoperative complications (n) | 18 (27.7%) | 3 (3.4%) | <0.001 |
| Multifocal tumor (n) | 24 (36.9%) | 19 (21.8%) | 0.041 |
| Bilateral tumor (n) | 22 (33.8%) | 17 (19.5%) | 0.046 |
| Major tumor size ˃2 cm (n) | 26 (40.0%) | 28 (32.2%) | 0.319 |
| Total tumor size ˃2 cm (n) | 30 (46.2%) | 35 (40.2%) | 0.465 |
| Capsular invasion (n) | 31 (47.7%) | 16 (18.4%) | <0.001 |
| Extrathyroidal invasion (n) | 12 (18.5%) | 5 (5.7%) | 0.014 |
| LNR ˃1/3 (n) | 29 (44.6%) | 11 (12.6%) | <0.001 |
MTC: medullary thyroid carcinoma; LNM, lymph node metastases; BMI: body mass index; CEA: carcinoembryonic antigen; ASA: American Society of Anesthesiologists; LNR: lymph node ratio.