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. 2022 Feb 9;13:753570. doi: 10.3389/fimmu.2022.753570

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Copyright © 2022 Scott, Prabhakara, Walters, Olson and Cox

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytokine ELISAs. The above charts depict the average concentration of TNF-⍺ (A), IL-17 (B), and IL-1β (C) detected in cerebral tissue culture from individual ELISAs. TNF-⍺ concentrations were mostly equivalent across all groups. The female groups recorded higher IL-17 concentrations than the male groups, but there was no significant difference between the female CCI group and the female sham group (B). IL-1β concentrations were elevated in the CCI groups, but there was no significant difference between the female CCI or male CCI groups (C). **p < 0.005.