Figure 1.

Set-up of the magnet-induced PU on the dorsal skinfold of mice. (a,b) Upon tamoxifen induction, the confetti transgene will be recombined specifically in Pax7 + cells, to express one of the following four proteins: GFP^nuc with a nuclear localization signal, cytoplasmic YFP^cyt, cytoplasmic RFP^cyt or membrane-targeted (upon fusion, sarcolemma-targeted) CFP^mem. Upside-down text indicates antisense genes not expressed. (c) Experimental schedule of PU induction and sacrifice for tissue harvest. Tamoxifen is injected two weeks prior to magnet placement.