Key Table: Table 1.

List of QTGs and QTVs discovered in C. elegans^a

Phenotype	Mapping type	QTG	QTV	Refs
Natural wild isolate alleles
Genetic perturbation (vulval induction, gene expression)	Linkage mapping	amx-2	NA	[50,51]
PolyQ aggregation	Linkage mapping	atg-5	NA	[150]
Drug response (albendazole)	Association mapping	ben-1	NA	[70]
Drug response (arsenic trioxide)	Association mapping; linkage mapping	dbt-1	C78S	[76]
Orsay virus sensitivity	Association mapping	drh-1	Deletion	[101]
Dauer formation	Linkage mapping	eak-3	Deletion	[41]
Aggregation; bordering	Linkage mapping	exp-1	NA	[90]
Drug response (abamectin); pathogen response (Streptomyces avermitilis)	Association mapping; linkage mapping	glc-1	Deletion	[8,65]
Drug response (proprionate)	Association mapping	glct-3	G19stop; F19fs	[74]
Matricidal hatching	Linkage mapping	kcnl-1	V530L	[100]
Male tail morphology	Linkage mapping	mab-23	C38F	[47,48]
Embryonic lethality	Linkage mapping	peel-1 zeel-1	Deletion	[113]
Nictation	Linkage mapping	piRNA	NA	[93]
Male-male plugging behavior	Linkage mapping	plep-1	V278D	[92]
Copulatory plugging; embryonic lethality	Linkage mapping	plg-1	TE insertion	[96]
Telomere length	Association mapping	pot-2	NA	[108]
RNAi sensitivity	BSA; linkage mapping	ppw-1	NA	[103,104]
Competitive fitness	BSA	rcan-1	CNV	[95]
Drug response (amsacrine, bleomycin, bortezomib, carmustine, cisplatin, etoposide, puromycin, silver); gene expression	Linkage mapping	scb-1	NA	[67,68]
Temperature-induced sterility	BSA; linkage mapping	set-24	Deletion	[20]
Drug response (zinc)	Association mapping; linkage mapping	sqst-5	Deletion	[6]
Pheromone response (dauer formation)	Association mapping	srg-37	Deletion	[39]
Pheromone sensitivity	Linkage mapping	srx-43	NA	[86]
Drug response (abamectin); stress resistance (H2O2); fitness; gene expression	BSA	sti-1	NA	[73]
Embryonic lethality	BSA	sup-35 pha-1	NA	[98]
Drug response (etoposide, amsacrine)	Association mapping; linkage mapping	top-2	Q797M	[75]
Temperature response (body size)	Linkage mapping	tra-3	F96L	[38]
Food foraging response	Linkage mapping	tyra-3	NA	[81]
Laboratory-adapted alleles
Genetic perturbation (movement); body size	Linkage mapping	col-182	Deletion	[49]
Oxygen sensing; oxygen response	Linkage mapping	glb-5	Insertion	[84,85]
Vulval induction	Linkage mapping	nath-10	I746M	[37]
Clumping; pathogen avoidance (Pseudomonas aeruginosa, Staphylococcus aureus); pathogen response (Bacillus thuringiensis); fecundity; body size; oxygen response	Linkage mapping	npr-1	V215F	[17,63,64,84,85,94]
Reproductive timing; lifespan; dauer formation; growth rate; fecundity	Linkage mapping	nurf-1	Deletion	[18,19]
Competitive fitness	BSA	rcan-1	CNV	[95]
Dauer formation	Linkage mapping	scd-2	G985R; G1174E	[43]
Dauer formation	Linkage mapping	srg-36 srg-37	Deletion	[44]

^aAbbreviations: BSA, bulk-segregant analysis; CNV, copy number variation; NA, not available; QTG, quantitative trait genes; QTV, quantitative trait variants; TE, transposable elements.