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. 2022 Feb 23;18(2):20210371. doi: 10.1098/rsbl.2021.0371

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© 2022 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 1. — Brain areas involved in pathogen recognition and avoidance by rodents. The red circle represents vasopressin receptors and the blue circle represents TRH receptors. Although several neurochemicals have been identified to be involved in pathogen recognition and avoidance (oxytocin, opioids, serotonin, dopamine, endocannabinoids, glucocorticoids, various immune components, oestrogens and progesterone), their brain sites of action and the receptors mediating those effects remain unknown. In dashed lines are likely candidate regions. MOS = main olfactory bulb; AOS = accessory olfactory system; PFC = pre-frontal cortex; IC = insular cortex; BNST = bed nucleus of the stria terminalis; MeA = medial amygdala; CoApm = posteromedial nucleus of the cortical-amygdala.