Table 1.
Gene Ontology Terms Enriched for Different Clusters
| Cluster | Adj.p | Pathways |
|---|---|---|
| A | 3.00E-17 | Endoplasmic reticulum unfolded protein response |
| A | 1.93E-16 | Response to endoplasmic reticulum stress |
| A | 1.20E-15 | Response to unfolded protein |
| A | 1.20E-15 | Cellular response to unfolded protein |
| A | 2.43E-15 | Response to topologically incorrect protein |
| A | 2.48E-14 | Cellular response to topologically incorrect protein |
| A | 5.93E-09 | IRE1-mediated unfolded protein response |
| A | 8.19E-06 | Carboxylic acid metabolic process |
| A | 9.96E-06 | Oxoacid metabolic process |
| A | 1.29E-04 | ER-nucleus signaling pathway |
| A | 1.35E-04 | Organic substance transport |
| A | 1.62E-04 | PERK-mediated unfolded protein response |
| A | 4.27E-04 | Protein exit from endoplasmic reticulum |
| A | 4.27E-04 | Golgi vesicle transport |
| B | 7.97E-31 | Anatomical structure morphogenesis |
| B | 4.46E-28 | Cell migration |
| B | 2.07E-27 | Movement of cell or subcellular component |
| B | 2.04E-26 | Regulation of developmental process |
| B | 2.65E-26 | Cell motility |
| B | 4.25E-25 | Locomotion |
| B | 2.67E-24 | Tissue development |
| B | 8.43E-23 | Cellular developmental process |
| B | 2.62E-22 | Regulation of cell migration |
| B | 6.94E-22 | Regulation of multicellular organismal process |
| B | 7.77E-22 | Regulation of cell motility |
| B | 2.64E-21 | Animal organ development |
| B | 3.38E-21 | Cell differentiation |
| B | 3.73E-21 | Regulation of signaling |
| C | 1.44E-24 | Response to cytokine |
| C | 8.86E-24 | Immune system process |
| C | 1.93E-23 | Cellular response to chemical stimulus |
| C | 2.21E-23 | Defense response |
| C | 5.56E-23 | Response to organic substance |
| C | 5.58E-22 | Response to virus |
| C | 5.58E-22 | Cellular response to organic substance |
| C | 6.63E-22 | Cellular response to cytokine stimulus |
| C | 5.98E-21 | Response to stress |
| C | 1.89E-20 | Regulation of multicellular organismal process |
| C | 5.45E-20 | Response to external stimulus |
| C | 5.45E-20 | Defense response to virus |
| C | 3.05E-19 | Positive regulation of response to stimulus |
| C | 4.27E-19 | Positive regulation of multicellular organismal process |
| C | 7.77E-19 | Cell proliferation |
| D | 5.83E-51 | Response to cytokine |
| D | 4.71E-49 | Response to external biotic stimulus |
| D | 9.40E-48 | Cytokine-mediated signaling pathway |
| D | 4.51E-46 | Defense response |
| D | 1.20E-45 | Cellular response to cytokine stimulus |
| D | 2.07E-41 | Immune response |
| D | 1.27E-39 | Immune system process |
| D | 2.37E-37 | Response to external stimulus |
| D | 2.47E-32 | Cellular response to organic substance |
| D | 4.94E-32 | Response to organic substance |
| D | 2.22E-30 | Multiorganism process |
| D | 1.06E-29 | Response to stress |
| D | 1.59E-29 | Inflammatory response |