TABLE 2.
Characteristics of the case and control patients in the nationwide cohort
Dementia cases (N = 4849) | Controls (N = 48,506) | |
---|---|---|
Male sex, n (%) | 2299 (47.4) | 22,998 (47.4) |
Age, n (%) | ||
< 70 years | 1278 (26.4) | 12,784 (26.4) |
70–80 years | 2268 (46.8) | 22,688 (46.8) |
80–90 years | 1260 (26.0) | 12,612 (26.0) |
> 90 years | 43 (0.9) | 422 (0.9) |
Diabetes duration, median (IQR) a , b | 6.0 (3.0–10.0) | 6.0 (3.0–9.0) |
GLP‐1 RAs, n (%) | ||
0 years | 4575 (94.3) | 44,594 (91.9) |
1–2 years | 59 (1.2) | 623 (1.3) |
2–3 years | 35 (0.7) | 586 (1.2) |
3–4 years | 35 (0.7) | 483 (1.0) |
4–5 years | 74 (1.5) | 1076 (2.2) |
Stroke, n (%) b | 760 (15.7) | 5628 (11.6) |
Myocardial infarction, n (%) b | 527 (10.9) | 5241 (10.8) |
Hypertension, n (%) b | 3252 (67.1) | 31,961 (65.9) |
Chronic renal disease, n (%) b | 233 (4.8) | 2287 (4.7) |
Educational attainment, n (%) b , c | ||
Basic | 2490 (51.4) | 23,920 (49.3) |
Medium | 1508 (31.1) | 14,971 (30.9) |
Advanced | 427 (8.8) | 4681 (9.7) |
Years since initiation of second‐line diabetes treatment.
At beginning of 5‐year exposure window.
Educational status unknown in 424 (8.7%) cases and in 4934 (10.2%) controls.
Abbreviations: GLP‐1 RA, glucagon‐like peptide‐1 receptor agonist; IQR, interquartile range.