Table 2. Primary and Secondary Outcomes in a Study of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment in Refractory Out-of-Hospital Cardiac Arrest.
No. (%) | Absolute difference, % (95% CI) | P value | ||
---|---|---|---|---|
Invasive strategy (n = 124) | Standard strategy (n = 132) | |||
Primary outcome | ||||
Survival with minimal or no neurologic impairment at 180 da | 39 (31.5) | 29 (22.0) | 9.5 (−1.3 to 20.1) | .09 |
Secondary outcomes | ||||
Survival with minimal or no neurologic impairment at 30 da | 38 (30.6) | 24 (18.2) | 12.4 (1.9 to 22.7) | .02 |
Cardiac recovery at 30 db | 54 (43.5) | 45 (34.1) | 9.4 (−2.5 to 21) | .12 |
Defined as Cerebral Performance Category 1 or 2. The Cerebral Performance Category schema ranges from 1 (defined as conscious, alert, able to work), 2 (conscious, sufficient cerebral function for independent activities of daily life, able to work in sheltered environment), 3 (conscious, dependent on others for daily support), 4 (comatous, vegetative state) to 5 (defined as brain death). All patients observed to death or 180 days.
Defined as absence of both pharmacological and mechanical cardiac support for at least 24 hours.