Table 2. Crude ORs of Severe Maternal Morbidity and Postpartum Hemorrhage Associated With Neuraxial Analgesia for Vaginal Delivery Before Inverse Propensity Score Weighting (New York Hospitals, 2010-2017).
| Variable | No neuraxial analgesia | Neuraxial analgesia | Risk difference, % (95% CI)a | Crude OR (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|
| Women, No. | Events, No. | Incidence, % (95% CI) | Women, No. | Events, No. | Incidence, % (95% CI) | |||
| All women | ||||||||
| SMM | 302 603 | 4226 | 1.40 (1.36 to 1.44) | 272 921 | 3486 | 1.28 (1.23 to 1.32) | −0.12 (−0.17 to −0.07) | 0.91 (0.87 to 0.96) |
| PPH | 302 603 | 9889 | 3.27 (3.20 to 3.33) | 272 921 | 9269 | 3.40 (3.33 to 3.46) | 0.13 (0.06 to 0.21) | 1.04 (1.01 to 1.07) |
| Non-Hispanic White women | ||||||||
| SMM | 118 533 | 1129 | 0.95 (0.90 to 1.01) | 139 743 | 1412 | 1.01 (0.96 to 1.06) | 0.06 (−0.01 to 0.12) | 1.06 (0.98 to 1.15) |
| PPH | 118 533 | 3623 | 3.06 (2.96 to 3.17) | 139 743 | 4389 | 3.14 (3.05 to 3.23) | 0.08 (−0.03 to 0.19) | 1.03 (0.98 to 1.08) |
| Racial and ethnic minority womenb | ||||||||
| SMM | 181 688 | 3078 | 1.69 (1.63 to 1.75) | 132 354 | 2067 | 1.56 (1.50 to 1.63) | −0.13 (−0.21 to −0.06) | 0.92 (0.87 to 0.97) |
| PPH | 181 688 | 6199 | 3.41 (3.33 to 3.50) | 132 354 | 4866 | 3.68 (3.58 to 3.78) | 0.27 (0.15 to 0.37) | 1.08 (1.04 to 1.12) |
| Low-risk women (CMI-OB = 0) | ||||||||
| SMM | 214 471 | 2329 | 1.09 (1.04 to 1.13) | 185 875 | 1819 | 0.98 (0.93 to 1.02) | −0.11 (−0.16 to −0.05) | 0.90 (0.85 to 0.96) |
| PPH | 214 471 | 6358 | 2.96 (2.89 to 3.04) | 185 875 | 5579 | 3.00 (2.92 to 3.08) | 0.04 (−0.05 to 0.13) | 1.01 (0.98 to 1.05) |
| High-risk women (CMI-OB ≥1) | ||||||||
| SMM | 88 132 | 1897 | 2.15 (2.06 to 2.25) | 87 046 | 1667 | 1.91 (1.82 to 2.01) | −0.24 (−0.35 to −0.13) | 0.89 (0.83 to 0.95) |
| PPH | 88 132 | 3531 | 4.01 (3.88 to 4.14) | 87 046 | 3690 | 4.24 (4.11 to 4.37) | 0.23 (0.08 to 0.39) | 1.06 (1.01 to 1.11) |
Abbreviations: CMI-OB, comorbidity index for obstetric patients; OR, odds ratio; PPH, postpartum hemorrhage; SMM, severe maternal morbidity.
a
95% CI estimated using bootstrap with replacement (B = 2000) and the percentile method.
b
Racial and ethnic minority women included the following categories: Asian or Pacific Islander, Black, Hispanic, Native American, and other. Information on race or ethnicity was missing for 3206 hospitalizations.