Table 1A.

Patient sample information.

Patient Sample	AML42	AML218	AML224	AML237	AML238
Genetics	p53 mutant, NRAS mutant	FLT3 wt, IDH1/2 wt, CEBPα wt	FLT3 ITD; mutNPM1	mutNMP1	ND
Karyotype	Trisomy 8	Normal	ND	ND	ND
Diagnosis	MDS to AML	CMML-2	AML NOS	AML with mutated NPM1	Refractory MDS/AML
Pretreatment	No response to Aza/procrit, currently on hydroxyurea	ND	Naïve	ND	Revlimid, vidaza
% Blasts pretreatment	93	49	95	87	54
Total blasts pretreatment	9379	6046	25279	12879	2049