Table 1B.
Patient sample information.
| Patient Sample | AML293 | AML294 | AML295 | AML299 | AML303 |
|---|---|---|---|---|---|
| Genetics | NMP1 WT/FLT3 WT; KMTA2A normal | NMP1 mut;FLT3 WT | kmt2a rearrangement at 11q23, t(11;19) (q23;p13.1) | MLL-AF9 translocation at t(9;11) (p22;q23) | FLT3 WT;KRAS; 46, XX,t(6;11) (q27;q23) |
| Karyotype | ND | ND | ND | ND | ND |
| Diagnosis | AML NOS | AML | AML | Relapsed AML | Secondary AML, treatment-related |
| Age | 18 | ND | 71 | 31 | 57 |
| Sex | M | ND | ND | M | F |
| CD14 Status | Negative | ND | ND | Positive | Negative |
| Pretreatment | Naïve | Naïve | ND | 3+7, BMT, Relapsed | ND |
| % Blasts pretreatment | 93 | 77 | 83 | 96 | 79 |
| Total blasts pretreatment | 10,693 | 23,655 | 14,482 | 28,855 | 1,842 |