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. 2022 Feb 11;25(4):123. doi: 10.3892/mmr.2022.12639

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Copyright: © Liang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 9. — Knockdown of DDX11-AS1 inhibits the proliferation of breast cancer cells by targeting miR-497. Reverse transcription-quantitative PCR assay detected the expression of miR-497 in (A) MCF-7 and (B) MDA-MB-231 cells after transfection. ***P<0.001 vs. Inhibitor-NC. MTT detected cell viability in (C) MCF-7 and (D) MDA-MB-231 cells. Colony formation assay was used to detect the reproductive capacity of (E) MCF-7 and (F) MDA-MB-231 cells. Clones were counted. **P<0.05, ***P<0.001 vs. Control; ^#P<0.05, ^##P<0.01, ^###P<0.001 vs. shRNA-DDX11-AS1 + inhibitor-NC. DDX11-AS1, DDX11 antisense 1; miR-497, microRNA-497; NC, negative control; shRNA, short hairpin RNA.