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. Author manuscript; available in PMC: 2022 Feb 23.
Published in final edited form as: Annu Rev Biomed Eng. 2021 May 11;23:517–546. doi: 10.1146/annurev-bioeng-112619-044026

Table 1.

Clinical trials involving usage of stem cells from diverse origins to treat different liver diseases

Cell types incorporated Trial status Clinical trials reference
Autologous bone marrow MSCs for liver cirrhosis Recruiting NCT03626090
Autologous CD133 endothelial progenitor cells for liver cirrhosis Recruiting NCT03109236
Skin-derived ABCB5-positive MSCs for acute-on-chronic liver failure Recruiting NCT03860155
Human umbilical cord MSCs for decompensated HBV cirrhosis Recruiting NCT03826433
Umbilical cord–derived MSCs for decompensated liver cirrhosis Recruiting NCT03626090
Cellgram™ (bone marrow–derived MSCs) Recruiting NCT03838250
Allogeneic umbilical cord MSCs for liver cirrhosis caused by HBV Recruiting NCT04357600
Umbilical cord–derived MSCs for biliary atresia Recruiting NCT04522869
MSCs and T regulatory cells for decompensated cirrhosis Not yet recruiting NCT03460795
MSCs for acute-on-chronic liver failure Not yet recruiting NCT03863002
Stem cells from human exfoliated deciduous teeth for HBV-related liver cirrhosis Not yet recruiting NCT03957655
Bone marrow mononuclear stem cells for children suffering from liver cirrhosis due to biliary atresia Recruiting NCT03468699
Biomarker analysis of sinusoidal obstruction syndrome Active, not recruiting NCT03132337
Allogenic hematopoietic stem cells for HBV immunity Enrolling by invitation NCT03511794

Abbreviations: HBV, hepatitis B virus; MSC, mesenchymal stem cell.