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. 2021 May 13;218(4):iyab073. doi: 10.1093/genetics/iyab073

Figure 3.

Figure 3

sqv-6 is necessary for correct NMJ organization. (A) Confocal images of MADD-4-tagRFPt knock-in (magenta) at the DNC of control (left) and sqv-6(dz165) (right) worms. Quantifications show the MADD-4 fluorescence intensity at DNC in each genotype and results of Mann–Whitney test. (B) Confocal images of L-AChRs (UNC-29-tagRFPt knock-in, magenta) and cholinergic (ACh) boutons (SNB-1-BFP, green) at the DNC of control (left) and sqv-6(dz165) (right) worms. Quantifications show the L-AChR fluorescence intensity at DNC in each genotype and results of Mann–Whitney test. (C) Confocal images of GABARs (UNC-49-tagRFPt knock-in, magenta) and GABA boutons (SNB-1-GFP, green) at the DNC of control (left) and sqv-6(dz165) (right) worms. Quantifications show the GABAR fluorescence intensity at DNC in each genotype and results of Mann–Whitney test. Scale bars, 5 µm.