Table 1.
Genes that respond in parallel to caspofungin and Cup9
| ORF ID | Gene symbol | Fold change Wt +caspo/Wt—caspo | Fold change cup9 +caspo/Wt +caspo | Signal peptide |
|---|---|---|---|---|
| orf19.2034 | — | >60 | 0.06 | — |
| orf19.3499 | — | 54.85 | 0.17 | x |
| orf19.6486 | LDG3 | 48.32 | 0.15 | x |
| orf19.937 | — | 24.55 | 0.28 | x |
| orf19.5302 | PGA31 | 23.66 | 0.41 | x |
| orf19.5303 | PGA30 | 18.41 | 0.33 | x |
| orf19.1539 | — | 17.30 | 6.26 | — |
| orf19.36.1 | — | 17.16 | 0.25 | — |
| orf19.1171 | — | 14.92 | 0.43 | x |
| orf19.5399 | IFF11 | 13.92 | 0.37 | x |
| orf19.5874 | — | 13.16 | 0.11 | x |
| orf19.4082 | DDR48 | 12.36 | 0.48 | — |
| orf19.1524 | SPR3 | 9.82 | 0.31 | — |
| orf19.2160 | NAG4 | 8.74 | 0.40 | — |
| orf19.6475 | — | 7.45 | 0.31 | x |
| orf19.4688 | DAG7 | 7.42 | 0.32 | x |
| orf19.7170 | — | 7.28 | 0.35 | x |
| orf19.2252 | — | 6.27 | 0.12 | — |
| orf19.2809 | CTN3 | 5.48 | 0.50 | — |
| orf19.1048 | IFD6 | 5.14 | 0.37 | — |
| orf19.2593 | BIO2 | 4.92 | 0.38 | — |
| orf19.3643 | — | 4.50 | 0.33 | — |
| orf19.1440.1 | — | 4.26 | 0.41 | — |
| orf19.5975 | — | 3.71 | 0.36 | — |
| orf19.4255 | ECM331 | 2.94 | 0.42 | x |
| orf19.938 | — | 2.89 | 0.43 | — |
| orf19.4934 | OP4 | 2.76 | 0.44 | x |
| orf19.1440.2 | — | 2.60 | 0.43 | — |
| orf19.24 | RTA2 | 2.57 | 0.34 | — |
| orf19.3710 | YHB5 | 2.48 | 0.46 | — |
| orf19.3375 | — | 2.43 | 0.38 | x |
| orf19.555 | — | 2.41 | 0.16 | x |
| orf19.1868 | RNR22 | 2.39 | 0.49 | — |
| orf19.6837 | FMA1 | 2.35 | 0.44 | — |
| orf19.4936.1 | — | 2.28 | 0.47 | — |
| orf19.851 | — | 2.17 | 0.24 | x |
| orf19.5542 | SAP6 | 2.09 | 0.22 | x |
| orf19.17 | SCP1 | 2.08 | 0.43 | — |
| orf19.5144 | PGA28 | 2.03 | 0.22 | x |
| orf19.7557 | FGR46 | 2.02 | 0.44 | x |
| orf19.3794 | ZAP1/CSR1 | 0.48 | 2.85 | — |
| orf19.1930 | CFL5 | 0.45 | 3.20 | x |
| orf19.5141 | — | 0.35 | 4.27 | x |
| orf19.3895 | CHT2 | 0.24 | 8.74 | x |
| orf19.6142 | — | 0.21 | 7.08 | — |
| orf19.3112 | ZRT1 | 0.17 | 2.44 | x |
| orf19.3111 | PRA1 | 0.16 | 2.83 | x |
| orf19.2038 | — | 0.15 | 3.61 | — |
Genes that are caspofungin-induced and Cup9-activated or caspofungin-repressed and Cup9-repressed are listed. Complete differentially expressed gene analysis is in Supplementary Table S3. Genes whose products have a predicted signal peptide are indicated.