Figure 1.

Predictive performance of plasma polyamines. A, Schematic of polyamine pathway. Polyamines highlighted in red represent those polyamines quantified in plasma of patients with multiple endocrine neoplasia type 1 (MEN1). B, Area under the receiver operating characteristic curve (AUC [95% CI]) of individual polyamines for distinguishing MEN1 patients with distant metastatic duodenopancreatic neuroendocrine tumors (dpNETs) (cases; n = 14) from MEN1 patients with indolent dpNETs and without distant or regional metastases (control 1; n = 28) as well as MEN1 patients without dpNETs (control 2; n = 14) in test set 1.