Figure 2.

Metabolic outcomes across age categories in a cohort of patients with classic congenital adrenal hyperplasia. Shown are (A) obesity, defined as BMI ≥ 85th percentile for <2 years, ≥95th percentile 2 to <18 years, or BMI ≥ 30 kg/m² for ≥18 years; (B) hypertension (stage 1 and 2) based on the American Academy of Pediatrics’s 2017 guidelines for children and the American College of Cardiology/American Heart Association 2017 Task Force for Adults (11,12); (C) insulin resistance based on HOMA-IR: ≥2.5 in adults or ≥3.16 in adolescents (≥12 years) (13,14); (D) fasting hyperglycemia (blood glucose ≥100); (E) dyslipidemia (based on NHANES percentiles for age and sex in children and specific targets for adults based on sex) (17,18).